Importance of symptoms acuity for clinical diagnosis of primary sellar atypical teratoid/rhabdoid tumor

Table 1 Primary sellar atypical teratoid/rhabdoid tumor cases confirmed by molecular studies

Ref.	Age	Sex	Molecular diagnosis	Headache duration	Visual symptoms duration	Pituitary hormones	Imaging features	Surgery	Chemotherapy	Radiation	Outcome
Zamudio-Coronado et al[23], 2023	60	F	Loss of INI1 SMARCB1 mutations	No headache	2 months	Normal	1.3 cm with cavernous sinus invasion	Total resection, rapid recurrence	Yes	Yes	Did not specify
Aldhafeeri et al[24], 2023	32	M	Loss of INI1	4 days	ND	Hypopituitarism	Large sellar mass with suprasellar distension	Debulking	No	No	Died 3 months after presentation
Yu[14], 2023	45	F	Loss of INI1 (Met)	3 weeks	1 week	Hypopituitarism	1.9 cm × 2.2 cm × 1.8 cm	Debulking	No	No	Alive 1 month after presentation
Yu[14], 2023	32	F	Loss of INI1 (Met)	1 month	1 week	Normal	2.1 cm	Debulking	No	Yes	Died 4 months after presentation
Baiano et al[25], 2022	32	F	Loss of INI1 (Met)	2 months	10 days	Elevated prolactin	Large	Debulking	Yes	No	Died 2 months after presentation
Baiano et al[25], 2022	42	F	Loss of INI1 (Met)	Intense	ND	ND	Large	Debulking	Yes	No	Died 2 months after presentation
Baiano et al[25], 2022	41	F	Loss of INI1 (Met)	ND	ND	Hypopituitarism	Large	Debulking	No	No	Died 1 month after presentation
Baiano et al[25], 2022	50	F	Loss of INI1	Intense	ND	Hypopituitarism	Large	Debulking	Yes	No	Alive 18 months after presentation
Major et al[11], 2022	70	F	Loss of INI1	3 months	4 months	ND	1.8 cm × 2.2 cm × 1.7 cm	Debulking	Yes	Yes	Died 8.5 months after presentation
Duan et al[26], 2022	47	F	Loss of INI1 (Met)	ND	ND	6/7 have hypopituitarism	Large	Debulking	No	No	Died 6 months after presentation
Duan et al[26], 2022	52	F	Loss of INI1 (Met)	ND	ND	6/7 have hypopituitarism	Large	Debulking	No	No	Died 2.5 months after presentation
Duan et al[26], 2022	47	M	Loss of INI1 (Met)	ND	ND	6/7 have hypopituitarism	Large	Debulking	No	Yes	Died 1 month after presentation
Duan et al[26], 2022	46	F	Loss of INI1 (Met)	ND	ND	6/7 have hypopituitarism	Large	Debulking	No	No	Died 6 months after presentation
Duan et al[26], 2022	45	F	Loss of INI1 (Met)	ND	ND	6/7 have hypopituitarism	Large	Debulking	No	No	Died 1 month after presentation
Duan et al[26], 2022	73	F	Loss of INI1 (Met)	ND	ND	6/7 have hypopituitarism	Large	Debulking	No	No	Died 3 months after presentation
Duan et al[26], 2022	41	F	Loss of INI1 (Met)	ND	ND	6/7 have hypopituitarism	Large	Debulking	No	No	Alive 11 months after presentation
Fukuda et al[27], 2021	45	F	Loss of INI1	ND	A few weeks	Hypopituitarism	Large	Debulking	Yes	Yes	Died 5 months after presentation
Liu et al[28], 2020	43	F	Loss of INI1	1 month	1 month	Normal	4.5 cm	Debulking	No	Yes	Died 4 months after presentation
Liu et al[28], 2020	52	F	Loss of INI1	2 weeks	ND	Hypopituitarism	2.8 cm	Debulking	No	No	Died 2 months after presentation
Liu et al[28], 2020	50	F	Loss of INI1	2 months	2 months	Hypopituitarism	2.7 cm	Debulking	No	No	Died 1 month after presentation
Liu et al[28], 2020	29	F	Loss of INI1	4 months	ND	Hypopituitarism	1.9 cm	Debulking	Yes	Yes	Died 8 months after presentation
Liu et al[28], 2020	80	F	Loss of INI1	2 weeks	2 weeks	Hypopituitarism	2.2 cm	Debulking	No	No	Died 1 month after presentation
Bokhari et al[29], 2020	40	F	Loss of INI1	Severe	ND	ND	2.9 cm × 1.7 cm × 2.3 cm	Debulking	None	None	ND
Madhavan et al[30], 2020	58	F	Loss of INI1	ND	ND	Hypopituitarism	2.1 cm sellar mass with 3.1 cm suprasellar extension	Debulking	No	No	ND
Siddiqui et al[31], 2019	55	F	Loss of INI1	1 week	1 week	ND	3.5 cm × 1.7 cm	Debulking	No	No	Died 1 .5 months after presentation
Asmaro et al[32], 2019	62	F	Loss of INI1	Several months	ND	Hypopituitarism	Large	Debulking	No	No	Died 2 months after presentation
Lawler and Robertson[33], 2019	27	F	Loss of INI1	ND	ND	ND	Large	Debulking	ND	ND	ND
Su and Su[34], 2018	37	F	Loss of INI1	ND	2 months	ND	2.57 cm × 1.96 cm × 3.63 cm	Debulking	No	No	Died 3 months after presentation
Nishikawa et al[35], 2018	42	F	Loss of INI1	Rapid	Rapid	ND	1.9 cm × 2.0 cm	Debulking	Yes	Yes	Died 11 months after presentation
Barresi et al[36], 2018	59	F	Loss of INI1	Days	Days		2.3 cm × 1.2 cm	Debulking	No	No	Died 2 months after presentation
Paolini et al[37], 2018	31	F	Loss of INI1	ND	ND	ND	ND	Debulking	No	No	Died 2 months after presentation
Paolini et al[37], 2018	36	F	Loss of INI1	ND	ND	ND	ND	Debulking	Yes	Yes	Alive 22 months after presentation
Paolini et al[37], 2018	46	F	Loss of INI1	ND	ND	ND	ND	Debulking	No	No	Died after 2nd resection
Paolini et al[37], 2018	47	F	Loss of INI1	ND	ND	ND	ND	Debulking	Yes	Yes	Alive 62 months after presentation
Paolini et al[37], 2018	65	f	Loss of INI1	ND	ND	ND	ND	Debulking	Yes	Yes	Died 23 months after presentation
Johann et al[38], 2018	20	F	Loss of INI1 (met)	ND	ND	ND	ND	Debulking	Yes	No	Died 10 years after presentation
Johann et al[38], 2018	48	F	Loss of INI1 (Met)	ND	ND	ND	ND	Debulking	No	No	Alive 4 months after presentation
Huq et al[39], 2018	62	F	Loss of INI1	2 months	Finally	Hypopituitarism	Large	Debulking	No	No	Died 2 months after presentation
Pratt et al[40], 2017	47	F	Loss of INI1	Severe	ND	ND	2.6 cm × 3.9 cm × 3.2 cm	Debulking	No	Yes	ND
Nakata et al[41], 2017	31	F	Loss of INI1	ND	ND	ND	ND	Debulking	Yes	Yes	Died 28 months after presentation
Nakata et al[41], 2017	56	F	Loss of INI1	ND	ND	ND	ND	Debulking	No	Yes	Died 23 months after presentation
Nakata et al[41], 2017	44	F	Loss of INI1	ND	ND	ND	ND	Debulking	Yes	Yes	Died 17 months after presentation
Nakata et al[41], 2017	26	F	Loss of INI1	ND	ND	ND	ND	Debulking	Yes	Yes	Died 33 months after presentation
Nakata et al[41], 2017	21	F	Loss of INI1	ND	ND	ND	ND	Debulking	Yes	Yes	Died 35 months after presentation
Nakata et al[41], 2017	69	F	Loss of INI1	ND	ND	ND	ND	Debulking	Yes	Yes	Alive 37 months after presentation
Almalki et al[42], 2017	36	F	Loss of INI1	3 months	1 month	Hypopituitarism	Large	Debulking	Yes	Yes	Alive 3 years after presentation
Elsayad et al[43], 2016	66	M	Loss of INI1	ND	ND	ND	2.2 cm × 1.6 cm × 1.4 cm	Debulking	No	Yes	Alive 4 years after presentation
Larran-Escandon et al[44], 2016	43	F	Loss of INI1	3 months	2 weeks	Hypopituitarism	2.0 cm × 2.3 cm	Debulking	No	No	Died 1 month after presentation
Nobusawa et al[45], 2016	69	F	Loss of INI1 (Met)	ND	Nost specified. Progressed over a few days	ND	2.8 cm × 1.6 cm	Debulking	Yes	Yes	Alive 2 years after presentation
Lev et al[13], 2015	36	F	Loss of INI1	1 months	6 days	Hypopituitarism	3.3 cm × 3.2 cm × 2.3 cm	Debulking	Yes	Yes	Died 2.5 years after presentation
Biswas et al[46], 2015	48	F	Loss of INI1	ND	2 weeks	ND	ND	Debulking	Yes	Yes	Died 2 months after presentation
Regan et al[47], 2015	45	F	Loss of INI1	9 days	9 days	ND	Large	Debulking	No	Yes	Died 6 months after presentation
Park et al[48], 2014	42	F	Loss of INI1	ND	Progressive	ND	Large	Debulking	Yes	Yes	Alive 2 years after presentation
Shitara and Akiyama[49], 2014	44	F	Loss of INI1	ND	2 months	ND	Large	Debulking	Yes	Yes	Alive 17 months after presentation
Moretti et al[50], 2013	60	F	Loss of INI1	ND	ND	ND	Large	Debulking	Yes	Yes	Alive 30 months after presentation
Chou et al[51], 2013	43	F	Loss of INI1	10 days	10 days	ND	2 cm	Debulking	No	Yes	Alive at 2 weeks
Schneiderhan et al[52], 2011	61	F	Loss of INI1 (Met)	ND	ND	ND	2 cm	Debulking	No	No	Died 3 months after presentation
Schneiderhan et al[52], 2011	57	F	Loss of INI1	ND	ND	ND	2 cm	Debulking	Yes	Yes	Alive 6 months after presentation
Las Heras and Pritzker[53], 2010	46	F	Loss of INI1	ND	ND	ND	ND	Debulking	ND	ND	ND
Arita et al[54], 2008	56	F	Loss of INI1 (Met)	2 months	2 months	ND	2.5 cm	Debulking	No	Yes	Died 23 months after presentation
Raisanen et al[55], 2005	31	F	Loss of INI1	ND	ND	ND	1.6 cm	Debulking	No	Yes	Died 9 months after presentation
Raisanen et al[55], 2005	20	F	Loss of INI1	ND	ND	ND	2.0 cm	Debulking	Yes	Yes	Alive 28 months after presentation

F: Female; M: Male; Met: DNA methylation classification; ND: Not described; INI1: Integrase interactor 1; SMARCB1: Switch defective/sucrose non-fermentable related BAF chromatin remodeling complex subunit B1.