Natural compound rosmarinic acid displays anti-tumor activity in colorectal cancer cells by suppressing nuclear factor-kappa B signaling

Figure 1 Rosmarinic acid inhibits survival of colorectal cancer cells. A: Chemical structure of rosmarinic acid; B-G: HCT116 (B), HT29 (C), LoVo (D), RKO (E), SW480 (F), and SW620 (G) cells were separately incubated with increasing concentrations of rosmarinic acid. Twenty-four hours later, cells were prepared for Cell Counting Kit-8 assay to evaluate the cell viability. n = 3. Data are shown as the mean ± SD. ^aP < 0.001 vs group ‘0’, ^bP < 0.0001 vs group ‘0’. RA: Rosmarinic acid.