Toxicity of dose-escalated, hypofractionated helical tomotherapy for inoperable thoracic esophageal squamous cell carcinoma

doi:10.5306/wjco.v16.i5.101378

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May 24, 2025 (publication date) through Jun 16, 2025

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. May 24, 2025; 16(5): 101378
Published online May 24, 2025. doi: 10.5306/wjco.v16.i5.101378

Table 3 Ordinal logistic regression of esophageal toxicity

	Estimate	SE	Wald	P value	95% confidence interval
Dose level (Gy per fraction)	-0.96	1.14	0.70	0.40	-3.20, 1.28
EQD₂ (α/β = 10)	0.17	0.06	6.99	0.01	0.04, 0.29
Tumor classification	-0.12	0.37	0.11	0.74	-0.86, 0.61

EQD₂: Equivalent dose at 2Gy per fraction.

Citation: Zhang SM, Sun J, Pan XO, Zhu WC, Zhou YK. Toxicity of dose-escalated, hypofractionated helical tomotherapy for inoperable thoracic esophageal squamous cell carcinoma. World J Clin Oncol 2025; 16(5): 101378
URL: https://www.wjgnet.com/2218-4333/full/v16/i5/101378.htm
DOI: https://dx.doi.org/10.5306/wjco.v16.i5.101378