Magistrelli P, D’Ambra L, Berti S, Bonfante P, Francone E, Vigani A, Falco E. Adult pulmonary blastoma: Report of an unusual malignant lung tumor. World J Clin Oncol 2014; 5(5): 1113-1116 [PMID: 25493248 DOI: 10.5306/wjco.v5.i5.1113]
Corresponding Author of This Article
Luigi D’Ambra, MD, Department of Surgery, POLL-ASL5, Via Vittorio Veneto 197, 19100 La Spezia, Italy. luigidambra68@libero.it
Research Domain of This Article
Surgery
Article-Type of This Article
Case Report
Open-Access Policy of This Article
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Prospero Magistrelli, Luigi D’Ambra, Stefano Berti, Pierfrancesco Bonfante, Elisa Francone, Emilio Falco, Department of Surgery, POLL-ASL5, 19100 La Spezia, Italy
Antonella Vigani, Department of Oncology, POLL-ASL5, 19100 La Spezia, Italy
Author contributions: Magistrelli P, D’Ambra L, Berti S, Bonfante P, Francone E, Vigani A and Falco E contributed equally to this work; Magistrelli P, Bonfante P and Falco E designed the report and performed the surgical intervention; D’Ambra L, Berti S, Francone E and Vigani A collected the patient’s clinical data; Magistrelli P wrote the paper; D’Ambra L, Berti S, Bonfante P, Francone E, Vigani A and Falco E revised the article; Magistrelli P, D’Ambra L, Berti S, Bonfante P, Francone E, Vigani A and Falco E read and approved the final version of the manuscript.
Correspondence to: Luigi D’Ambra, MD, Department of Surgery, POLL-ASL5, Via Vittorio Veneto 197, 19100 La Spezia, Italy. luigidambra68@libero.it
Telephone: +39-0187-533465 Fax: +39-0187-533257
Received: March 4, 2014 Revised: June 24, 2014 Accepted: August 27, 2014 Published online: December 10, 2014
Abstract
Pulmonary blastoma is an uncommon lung malignancy, usually presenting itself as a large chest mass causing pain, hemoptysis, cough and dyspnea; however, it is asymptomatic in up to 40% of patients. We present the case and suggestive images of a 37-year-old non-smoking lady with a monophasic pulmonary blastoma located in the lower lobe of the left lung who underwent a left posterolateral thoracotomy with lower lobectomy, hilar and mediastinal node dissection, followed by chemo and radiation therapy. After 36 mo, there is no disease progression and the patient is in good health, clinically stable and without significant chest pain.
Core tip: Pulmonary blastoma is a rare condition and diagnosis may be difficult to obtain. It is important to underline that the appropriate management of this unusual type of lesion can be achieved only by a multidisciplinary specialized team, able to plan the correct integrated strategy based on aggressive surgery and chemo-radiation therapy.
