Coeliac disease in the modern era: Severity of small bowel mucosal injury at diagnosis with analysis of clinical correlates and rate of improvement on a gluten free diet

Table 6 Symptoms, serology and histology results for 87 patients with repeat biopsy

Biopsy score1	Repeat biopsy score	Positive serology2	Reported gluten free diet adherence	Symptoms at repeat biopsy
0	31 (36)	Positive = 6	Yes = 31	Yes = 4
		Negative = 19	No = 0	No = 14
		Unknown = 6		Unknown = 13
1	17 (20)	Positive = 4	Yes = 16	Yes = 2
		Negative = 9	No = 1	No = 10
		Unknown = 4		Unknown = 5
2	5 (6)	Positive = 1	Yes = 5	Yes = 1
		Negative = 4	No = 0	No = 2
		Unknown = 0		Unknown = 2
3a	26 (30)	Positive = 4	Yes = 20	Yes = 3
		Negative = 17	No = 6	No = 12
		Unknown = 5		Unknown = 11
3b	1 (1)	Positive = 0	Yes = 1	Yes = 0
		Negative = 0	No = 0	No = 0
		Unknown = 1		Unknown = 1
3c	7 (8)	Positive = 4	Yes = 3	Yes = 1
		Negative = 1	No = 4	No = 4
		Unknown = 2		Unknown = 2

¹Marsh-Oberhuber score at diagnosis;

²Anti-transglutaminase antibodies or endomysial antibodies.