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©The Author(s) 2018.
World J Gastrointest Pharmacol Ther. Aug 7, 2018; 9(3): 22-30
Published online Aug 7, 2018. doi: 10.4292/wjgpt.v9.i3.22
Published online Aug 7, 2018. doi: 10.4292/wjgpt.v9.i3.22
Table 6 Summary of results of pharmacokinetic variables from analyses-of-variance: Lactulose 20 g (liquid) vs Water
| Liquid | Lactulose 20 g | Water 250 mL | Treatment difference | |||||
| Variable | n | LS mean | 95%CI | n | LS mean | 95%CI | Difference | 95%CI |
| iAUC (mmol/L*min) | 12 | 11.62 | (-3.21; 26.46) | 12 | 9.92 | (-4.92; 24.77) | 1.701 | (-15.29; 18.69) |
| AUC (mmol/L*min) | 12 | 886.03 | (852.58; 919.49) | 12 | 890.45 | (856.97; 923.93) | -4.419 | (-33.65; 24.82) |
| AUC_base (mmol/L*min) | 12 | -54.09 | (-87.55; -20.64) | 12 | -49.67 | (-83.15; -16.19) | -4.419 | (-33.65; 24.82) |
| C_max (mmol/L) | 12 | 5.57 | (5.33; 5.81) | 12 | 5.49 | (5.24; 5.73) | 0.083 | (-0.19; 0.36) |
| Max_increase (mmol/L) | 12 | 0.35 | (0.10; 0.59) | 12 | 0.26 | (0.02; 0.51) | 0.083 | (-0.19; 0.36) |
- Citation: Steudle J, Schön C, Wargenau M, Pauly L, Schwejda-Güttes S, Gaigg B, Kuchinka-Koch A, Stover JF. Blood glucose response after oral intake of lactulose in healthy volunteers: A randomized, controlled, cross-over study. World J Gastrointest Pharmacol Ther 2018; 9(3): 22-30
- URL: https://www.wjgnet.com/2150-5349/full/v9/i3/22.htm
- DOI: https://dx.doi.org/10.4292/wjgpt.v9.i3.22