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©The Author(s) 2018.
World J Gastrointest Pharmacol Ther. Aug 7, 2018; 9(3): 22-30
Published online Aug 7, 2018. doi: 10.4292/wjgpt.v9.i3.22
Published online Aug 7, 2018. doi: 10.4292/wjgpt.v9.i3.22
Table 4 Summary of results of pharmacokinetic variables from analyses-of-variance; Lactulose 20 g (crystals) vs Water
| Crystals | Lactulose 20 g | Water 250 mL | Treatment difference | |||||
| Variable | n | LS mean | 95%CI | n | LS mean | 95%CI | Difference | 95%CI |
| iAUC (mmol/L*min) | 12 | 12.51 | (-1.74; 26.76) | 12 | 7.74 | (-6.57; 22.05) | 4.772 | (-13.58; 23.12) |
| AUC (mmol/L*min) | 12 | 902.78 | (871.02; 934.53) | 12 | 896.86 | (865.03; 928.70) | 5.912 | (-21.48; 33.30) |
| AUC_base (mmol/L*min) | 12 | -20.47 | (-52.23; 11.28) | 12 | -26.39 | (-58.22; 5.45) | 5.912 | (-21.48; 33.30) |
| C_max (mmol/L) | 12 | 5.41 | (5.21; 5.62) | 12 | 5.36 | (5.16; 5.57) | 0.049 | (-0.20; 0.30) |
| Max_increase (mmol/L) | 12 | 0.28 | (0.08; 0.49) | 12 | 0.24 | (0.03; 0.44) | 0.049 | (-0.20; 0.30) |
- Citation: Steudle J, Schön C, Wargenau M, Pauly L, Schwejda-Güttes S, Gaigg B, Kuchinka-Koch A, Stover JF. Blood glucose response after oral intake of lactulose in healthy volunteers: A randomized, controlled, cross-over study. World J Gastrointest Pharmacol Ther 2018; 9(3): 22-30
- URL: https://www.wjgnet.com/2150-5349/full/v9/i3/22.htm
- DOI: https://dx.doi.org/10.4292/wjgpt.v9.i3.22