Combination therapy for inflammatory bowel disease

doi:10.4292/wjgpt.v8.i2.103

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 8, Issue 2

This Article

(430)

(520)

(0)

(9229)

(31)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Gastrointestinal Pharmacology and Therapeutics

ISSN

2150-5349

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

- Full Article with Cover (PDF)
- Full Article (XML)

Minireviews

World J Gastrointest Pharmacol Ther. May 6, 2017; 8(2): 103-113
Published online May 6, 2017. doi: 10.4292/wjgpt.v8.i2.103

Table 1 Author’s summary of the evidence for combination therapy

	Crohn’s disease		Ulcerative colitis
	Clinical benefit	Pharmacokinetic/immunogenic benefit	Clinical benefit	Pharmacokinetic/immunogenic benefit
IFX + AZA/6MP (treatment naïve)	+	+	+	+
IFX + AZA/6MP (step-up from immunomodulator monotherapy)	-	NA	NA	NA
IFX + MTX	+/-	+	NA	NA
ADA + IMM	+/-	+/-	NA	NA
VDZ + IMM	NA	+	NA	NA
Ustekinumab +	NA	NA	NA	NA
IMM	NA	NA	NA	NA

IFX: Infliximab; AZA: Azathioprine; 6-MP: 6-mercaptopurine; MTX: Methotrexate; ADA: Adalimumab; VDZ: Vedolizumab; IMM: immunomodulatory; +: beneficial; +/-: Possible benefit; NA: No adequate data available.

Full Size Table

Citation: Sultan KS, Berkowitz JC, Khan S. Combination therapy for inflammatory bowel disease. World J Gastrointest Pharmacol Ther 2017; 8(2): 103-113
URL: https://www.wjgnet.com/2150-5349/full/v8/i2/103.htm
DOI: https://dx.doi.org/10.4292/wjgpt.v8.i2.103

Sultan KS, Berkowitz JC, Khan S. Combination therapy for inflammatory bowel disease. World J Gastrointest Pharmacol Ther 2017; 8(2): 103-113 [PMID: 28533919 DOI: 10.4292/wjgpt.v8.i2.103]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.