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©The Author(s) 2016.
World J Gastrointest Pharmacol Ther. Nov 6, 2016; 7(4): 477-489
Published online Nov 6, 2016. doi: 10.4292/wjgpt.v7.i4.477
Published online Nov 6, 2016. doi: 10.4292/wjgpt.v7.i4.477
Table 3 Randomized controlled trials comparing radiofrequency ablation and percutaneous ethanol injection in hepatocellular carcinoma patients
| Ref. | Region | Patients (n) | Nodules n (1/>1) | Tumor size, cm | No. of sessions | Complete response (%) | 3-yr survival (%) | 3-yr recurrence (%) |
| Lin et al[65] | Taiwan | RFA (52) | 38/14 | 2.9 ± 0.8 | 1.6 ± 0.4 | 96.0 | 74 | 18.0 |
| PEI (52) | 40/12 | 2.8 ± 0.8 | 6.5 ± 1.6 | 88.0 | 50 | 45.0 | ||
| Lin et al[66] | Taiwan | RFA (62) | 49/13 | 2.5 ± 1.0 | 1.3 ± 0.3 | 96.1 | 74 | 14.0 |
| PEI (62) | 49/13 | 2.3 ± 0.8 | 4.9 ± 1.3 | 88.1 | 51 | 34.0 | ||
| Shiina et al[67] | Japan | RFA (118) | 72/46 | NA | 2.1 ± 1.3 | 100.0 | 81 | 1.7 |
| PEI (114) | 60/54 | NA | 6.4 ± 2.6 | 100.0 | 66 | 11.0 | ||
| Wang et al[68] | China | RFA (49) | NA | 2.4 ± 1.2 | NA | 93.8 | NA | NA |
| PEI (49) | NA | 2.3 ± 1.4 | NA | 77.5 | NA | NA | ||
| Azab et al[69] | Egypt | RFA (30) | NA | NA | 1.45 | 85.0 | NA | NA |
| PEI (30) | NA | NA | 7.68 | 75.0 | NA | NA | ||
| Giorgio et al[70] | Italy | RFA (128) | 128/0 | 2.3 ± 0.4 | 5.00 | 100.0 | 83 | 7.8 |
| PEI (143) | 143/0 | 2.2 ± 0.5 | 8.00 | 100.0 | 78 | 9.4 | ||
| Lencioni et al[71] | Italy | RFA (52) | 40/12 | 2.8 ± 0.6 | 1.1 ± 0.5 | 91.0 | NA | 21.0 |
| PEI (50) | 31/19 | 2.8 ± 0.8 | 5.4 ± 1.6 | 82.0 | NA | 59.0 | ||
| Brunello et al[72] | Italy | RFA (70) | 54/16 | 2.4 ± 0.5 | NA | 95.7 | 59 | NA |
| PEI (69) | 54/15 | 2.2 ± 0.5 | NA | 65.6 | 56 | NA |
- Citation: Facciorusso A, Serviddio G, Muscatiello N. Local ablative treatments for hepatocellular carcinoma: An updated review. World J Gastrointest Pharmacol Ther 2016; 7(4): 477-489
- URL: https://www.wjgnet.com/2150-5349/full/v7/i4/477.htm
- DOI: https://dx.doi.org/10.4292/wjgpt.v7.i4.477