Clinical update for the diagnosis and treatment of Clostridium difficile infection

doi:10.4292/wjgpt.v5.i1.1

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Feb 6, 2014 (publication date) through Apr 26, 2024

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World Journal of Gastrointestinal Pharmacology and Therapeutics

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2150-5349

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Pharmacol Ther. Feb 6, 2014; 5(1): 1-26
Published online Feb 6, 2014. doi: 10.4292/wjgpt.v5.i1.1

Table 3 Comparative average wholesale price for antibiotics used in the treatment of Clostridium difficile infection

Antibiotic	Cost per dose¹	Usual regimen	Cost per treatment¹
Metronidazole	$0.73
Vancomycin capsules (Vancocin HCL pulvules)	$31.83	125 mg 4 times/d × 10 d	$1273.20
Vancomycin intravenous formulation (generic)	$5.00/g ($0.62 per 125 mg dose)	125 mg 4 times/d × 10 d	$25.00
Fidaxomicin (Dificid)	$168.00	200 mg 2 times/d × 10 d	$3360.00
Rifaximin (Xifaxan)	$19.02 400 mg	400 mg 3 times/d × 20 d²	$1141.20

¹Average Wholesale Price (AWP); Anon, edition. Red Book online.

²Dose as a “chaser” after a course of oral vancomycin for recurrent CDI[151]. Via Drugdex System (internet database) Greenwood Village, CO: Thompson Healthcare, 2011[86]. CDI: Clostridium difficile infection.

Citation: IV ECO, III ECO, Johnson DA. Clinical update for the diagnosis and treatment of Clostridium difficile infection. World J Gastrointest Pharmacol Ther 2014; 5(1): 1-26
URL: https://www.wjgnet.com/2150-5349/full/v5/i1/1.htm
DOI: https://dx.doi.org/10.4292/wjgpt.v5.i1.1