Liver transplantation in adults: Choosing the appropriate timing

Table 1 General indications for liver transplantation

Acute liver failure

Complications of cirrhosis

Ascites

Encephalopathy

Synthetic dysfunction

Liver cancer

Refractory variceal hemorrhage

Chronic gastrointestinal blood loss due to portal hypertensive

gastropathy

Hepatopulmonary syndrome

Portopulmonary hypertension

Hepatorenal syndrome

Recurrent cholangitis

Intractable pruritus

Malnutrition

Hepatic myelopathy

Quality of life impairment

Metabolic disorders causing cirrhosis

Alpha-1-antitrypsin deficiency

Wilson disease

Nonalcoholic steatohepatitis and cryptogenic cirrhosis

Hereditary hemochromatosis

Tyrosinemia

Glycogen storage disease type IV

Metabolic disorders causing severe extrahepatic morbidity

Amyloidosis

Hyperoxaluria

Urea cycle defects

Disorders of branch chain amino acids

Miscellaneous conditions

Budd-Chiari syndrome

Metastatic neuroendocrine tumors

Polycystic disease

Biliary atresia

Alagille syndrome

Nonsyndromic paucity of the intrahepatic bile ducts

Cystic fibrosis

Progressive familial intrahepatic cholestasis