Hemodynamic safety of remimazolam vs propofol in elderly patients

Table 1 Baseline characteristics of the patients

Ref.	ASA grade	Procedure	Intervention	Control	Analgesia used	Number of PT in group (R)	Number of PT in group (P)	Age in group (R)	Age in group (P)	Sex (%) group (R)	Sex (%) group (P)
Liu et al[12], 2023	I-II	Gastrointestinal endoscopy	Remimazolam (0.10 mg/kg)	Propofol (1.5 mg/kg)	Sufentanil 5 μg	107	109	67.6 (5.7)	67.5 (4.9)	51 (47.7)	51 (46.8)
Chen et al[13], 2024	I-III	Gastrointestinal endoscopy	Remimazolam (6 mg/kg/hour)	Propofol (18 mg/kg/hour)		30	30	68.0 (67.0-72.3)	69.5 (66.0-72.0)	11 (36.7)	9 (30)
Chen et al[14], 2024	I-II	Gastroscopy	Remimazolam (0.17 mg/kg)	Propofol (1.112 mg/kg)	Sufentanil 0.1 μg/kg	122	118	71.9 (5.0)	71.7 (5.1)	66 (54)	62 (52.5)
Lin et al[15], 2024	I-III	Colonoscopy	Remimazolam (0.2 mg/kg)	Propofol (1 mg/kg)	Sufentanil 0.05 μg/kg	114	114	70 (67-75)	70 (68-75)	59 (51.8)	63 (55.3)
Ye et al[16], 2023	I-II	Gastroscopy	Remimazolam (0.2 mg/kg)	Propofol (2.0 mg/kg)	Remifentanil 0.2 μg/kg	64	65	68 (66-72)	68 (66-71)	39 (60.9)	36 (55.4)
Tan et al[17], 2022	I-II	Upper Gastrointestinal endoscopy	Remimazolam (0.2 mg/kg)	Propofol (1.0-1.5 mg/kg)	0.2 g lidocaine and butorphanol 0.01 mg/kg	33	33	65.5 (5.2)	66.2 (5.0)	22 (66.7)	21 (63.6)
Lu et al[18], 2022	I-III	Upper Gastrointestinal endoscopy	Remimazolam (300 mg/hour)	Propofol (3 g/hour)	Fentanyl citrate 50 μg	200	200	70.6 (4.7)	70.1 (4.5)	78 (39.0)	83 (46.5)
Guo et al[19], 2022	I-II	Gastrointestinal endoscopy	Remimazolam (0.15 mg/kg)	Propofol (1.5 mg/kg)	Alfentanil 5 μg/kg	39	38	70.4 (3.9)	69.1 (4.0)	25 (64)	22 (57.9)
Hu et al[20], 2022	I-III	Gastroscopy	Remimazolam (0.2 mg/kg)	Propofol (1.5mg/kg)	Sufentanil 0.1 μg/kg	173	173	70.11 (7.37)	69.92 (7.57)	69 (39.8)	72 (41.6)
Liu et al[21], 2021	I-II	Colonoscopy	Remimazolam (0.15 mg/kg)	Propofol (0.1 mL/kg)	Fentanyl citrate 0.5 μg/kg	115	117	68.87 (2.58)	69.12 (2.75)	54 (46.9)	58 (49.5)

ASA: American Society of Anesthesiologists; R: Remimazolam; P: Propofol; PT: Patient.