Fructose malabsorption associated with functional abdominal bloating: Case-control study

doi:10.4292/wjgpt.v17.i2.121264

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World Journal of Gastrointestinal Pharmacology and Therapeutics

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2150-5349

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Control Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Pharmacol Ther. Jun 5, 2026; 17(2): 121264
Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.121264

Table 2 Characteristics of the fructose hydrogen breath test among cases, n (%)/median (range)

S. No	Parameters	FHBT positive (n = 20)	FHBT negative (n = 50)	P value
1	FHBT - baseline H₂	6 (0-14)	6 (0-12)	0.70
2	FHBT - peak H₂	37 (22-124)	8 (0-27)	< 0.01
3	Methane - baseline	2 (1-9)	2 (1-16)	0.24
4	Methane - peak	4 (1-13)	3 (1-26)	< 0.01
5	Methane producers (CH₄ ≥ 3)	8 (40)	24 (48)	0.54
6	Symptoms during FHBT	16 (80)	31 (62)	0.14

FHBT: Fructose hydrogen breath test.

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Citation: Kulandaivelu A, Vaithiyam V, Mehta K, Reddy RT, Ahuja A, Sirohi N, Sonika U, Dalal A, Kumar A, Puri AS, Sachdeva S. Fructose malabsorption associated with functional abdominal bloating: Case-control study. World J Gastrointest Pharmacol Ther 2026; 17(2): 121264
URL: https://www.wjgnet.com/2150-5349/full/v17/i2/121264.htm
DOI: https://dx.doi.org/10.4292/wjgpt.v17.i2.121264

Kulandaivelu A, Vaithiyam V, Mehta K, Reddy RT, Ahuja A, Sirohi N, Sonika U, Dalal A, Kumar A, Puri AS, Sachdeva S. Fructose malabsorption associated with functional abdominal bloating: Case-control study. World J Gastrointest Pharmacol Ther 2026; 17(2): 121264 [PMID: 42273237 DOI: 10.4292/wjgpt.v17.i2.121264]

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