Clinical outcomes of upadacitinib dose escalation in inflammatory bowel disease: A single-center retrospective cohort study

doi:10.4292/wjgpt.v17.i2.120059

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 17, Issue 2

This Article

(27)

(28)

(0)

(688)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Gastrointestinal Pharmacology and Therapeutics

ISSN

2150-5349

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Pharmacol Ther. Jun 5, 2026; 17(2): 120059
Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.120059

Table 6 Endoscopic outcomes before and after dose escalation (paired observations), median (interquartile range)

Endoscopic outcome	Before	After	P value
Mayo endoscopic subscore	3 (2-5)	0 (0-0.5)	0.250
SES-CD	7 (5.5-9)	7 (4-9.5)	0.440

Mayo endoscopic subscore (ulcerative colitis); n = 3 paired observations. Simple endoscopic score for Crohn’s disease; n = 7 paired observations (6 non-zero paired differences included in Wilcoxon analysis). Values are presented as median (interquartile range). P values were calculated using the two-sided Wilcoxon signed-rank test. Given the small sample sizes, results should be interpreted with caution. SES-CD: Simple endoscopic score for Crohn’s disease.

Full Size Table

Citation: Ellington AL, Rambuss D, Barbina S, Chitnavis M. Clinical outcomes of upadacitinib dose escalation in inflammatory bowel disease: A single-center retrospective cohort study. World J Gastrointest Pharmacol Ther 2026; 17(2): 120059
URL: https://www.wjgnet.com/2150-5349/full/v17/i2/120059.htm
DOI: https://dx.doi.org/10.4292/wjgpt.v17.i2.120059

Ellington AL, Rambuss D, Barbina S, Chitnavis M. Clinical outcomes of upadacitinib dose escalation in inflammatory bowel disease: A single-center retrospective cohort study. World J Gastrointest Pharmacol Ther 2026; 17(2): 120059 [PMID: 42273244 DOI: 10.4292/wjgpt.v17.i2.120059]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.