Clinical outcomes of upadacitinib dose escalation in inflammatory bowel disease: A single-center retrospective cohort study

doi:10.4292/wjgpt.v17.i2.120059

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World Journal of Gastrointestinal Pharmacology and Therapeutics

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2150-5349

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Pharmacol Ther. Jun 5, 2026; 17(2): 120059
Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.120059

Table 1 Baseline characteristics of the study population, n (%)/mean ± SD/median (interquartile range)

Characteristic	Value
Age (years)	34 (26-46)
Female sex	24 (43)
Race/ethnicity
White	42 (75)
Black	8 (14)
Asian	3 (5)
Other	3 (5)
IBD subtype
Crohn’s disease	38 (68)
Ulcerative colitis	18 (32)
Prior biologic exposure	2.49 ± 1.25

IBD: Inflammatory bowel disease.

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Citation: Ellington AL, Rambuss D, Barbina S, Chitnavis M. Clinical outcomes of upadacitinib dose escalation in inflammatory bowel disease: A single-center retrospective cohort study. World J Gastrointest Pharmacol Ther 2026; 17(2): 120059
URL: https://www.wjgnet.com/2150-5349/full/v17/i2/120059.htm
DOI: https://dx.doi.org/10.4292/wjgpt.v17.i2.120059

Ellington AL, Rambuss D, Barbina S, Chitnavis M. Clinical outcomes of upadacitinib dose escalation in inflammatory bowel disease: A single-center retrospective cohort study. World J Gastrointest Pharmacol Ther 2026; 17(2): 120059 [PMID: 42273244 DOI: 10.4292/wjgpt.v17.i2.120059]

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