Copyright: ©Author(s) 2026.
World J Gastrointest Pharmacol Ther. Jun 5, 2026; 17(2): 118778
Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.118778
Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.118778
Table 8 Risk factors for postoperative recurrence in Crohn’s disease
| Risk factor | Effect on recurrence |
| Active cigarette smoking | Strongest modifiable predictor; higher endoscopic and surgical recurrence |
| Penetrating phenotype, perianal CD | Increased early endoscopic and clinical recurrence |
| Prior intestinal resection | Higher risk of further surgery and earlier recurrence |
| Extensive small-bowel resection | Increased recurrence and nutritional complications |
| Absence or delay of biologic prophylaxis | Higher endoscopic recurrence vs early anti-TNF therapy |
- Citation: Agrawal H, Gupta N. Surgical interventions in inflammatory bowel disease: Indications, techniques, outcomes, and future directions. World J Gastrointest Pharmacol Ther 2026; 17(2): 118778
- URL: https://www.wjgnet.com/2150-5349/full/v17/i2/118778.htm
- DOI: https://dx.doi.org/10.4292/wjgpt.v17.i2.118778