Copyright: ©Author(s) 2026.
World J Gastrointest Pharmacol Ther. Jun 5, 2026; 17(2): 118778
Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.118778
Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.118778
Table 7 Early surgery vs prolonged medical therapy in localized ileocaecal Crohn’s disease
| Aspect | Early ileocolic resection | Prolonged/optimized medical therapy (e.g., anti-TNF) |
| Primary aim | Rapid symptom control and removal of diseased segment | Long-term inflammation control and bowel preservation |
| Short-term outcomes | Faster symptom relief; fewer steroids; good QoL | Avoids surgical risk initially; some avoid surgery long-term |
| Long-term surgery need | Many will need further surgery over time | Substantial proportion ultimately require surgery |
| Strategy implications | Favored for stricturing/penetrating localized disease in fit patients | Favored when extensive small bowel involvement or high surgical risk |
- Citation: Agrawal H, Gupta N. Surgical interventions in inflammatory bowel disease: Indications, techniques, outcomes, and future directions. World J Gastrointest Pharmacol Ther 2026; 17(2): 118778
- URL: https://www.wjgnet.com/2150-5349/full/v17/i2/118778.htm
- DOI: https://dx.doi.org/10.4292/wjgpt.v17.i2.118778