Copyright: ©Author(s) 2026.
World J Gastrointest Pharmacol Ther. Jun 5, 2026; 17(2): 118778
Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.118778
Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.118778
Table 3 Ileal pouch-anal anastomosis vs permanent end ileostomy in ulcerative colitis
| Domain | IPAA (ileal pouch-anal anastomosis) | Permanent end ileostomy |
| Disease control | Removes colon/rectum; pouchitis common long-term | Removes colon/rectum; no pouchitis risk |
| Bowel function | 5-8 BMs/day, some urgency/soilage; improves over time | 4-6 stoma emptyings/day; predictable but appliance-dependent |
| Major complications | Pouchitis, pelvic sepsis, strictures, pouch failure | Parastomal hernia, skin problems, retraction/prolapse |
| Quality of life (global) | Generally “better or much better” than pre-op in > 80% of patients | Often improved vs pre-op; many report good HRQOL but with body-image issues |
| Sexual function | Small but real risk of pelvic nerve injury; most maintain function | Less pelvic dissection if rectum spared; function often preserved |
| Decisional aspects | More complex risk–benefit discussion; strong preference to avoid stoma | Some patients prefer predictable stoma to fear of pouch failure |
- Citation: Agrawal H, Gupta N. Surgical interventions in inflammatory bowel disease: Indications, techniques, outcomes, and future directions. World J Gastrointest Pharmacol Ther 2026; 17(2): 118778
- URL: https://www.wjgnet.com/2150-5349/full/v17/i2/118778.htm
- DOI: https://dx.doi.org/10.4292/wjgpt.v17.i2.118778