Copyright: ©Author(s) 2026.
World J Gastrointest Pharmacol Ther. Jun 5, 2026; 17(2): 118778
Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.118778
Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.118778
Table 2 Key surgical options in ulcerative colitis
| Procedure | Main indication | Advantages | Limitations/risks |
| Subtotal colectomy with end ileostomy | Emergency toxic megacolon, perforation, severe colitis | Rapid source control; avoids pelvic dissection | Permanent stoma if no later reconstruction; rectal stump issues |
| Total proctocolectomy + IPAA (J-pouch) | Medically refractory UC; dysplasia/cancer | No colon/rectum; continence preserved; no permanent stoma | Pouchitis, pelvic sepsis, sexual/urinary dysfunction, pouch failure |
| Total colectomy + ileorectal anastomosis | Mild rectal disease; fertility concerns; high-risk for IPAA | Easier operation, better pelvic nerve preservation | Ongoing rectal disease; cancer surveillance required |
| Permanent end ileostomy | Unfit for restorative surgery; failed pouch; patient choice | Technically straightforward; reliable symptom control | Body image concerns; stoma complications; appliance dependence |
- Citation: Agrawal H, Gupta N. Surgical interventions in inflammatory bowel disease: Indications, techniques, outcomes, and future directions. World J Gastrointest Pharmacol Ther 2026; 17(2): 118778
- URL: https://www.wjgnet.com/2150-5349/full/v17/i2/118778.htm
- DOI: https://dx.doi.org/10.4292/wjgpt.v17.i2.118778