Copyright: ©Author(s) 2026.
World J Gastrointest Pharmacol Ther. Jun 5, 2026; 17(2): 118778
Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.118778
Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.118778
Table 1 Indications for surgery in ulcerative colitis and Crohn’s disease
| Feature | Ulcerative colitis | Crohn’s disease |
| Main elective indication | Medically refractory pancolitis/proctitis despite optimized biologics | Fibro-stenotic obstruction, penetrating complications, failure of medical therapy |
| Cancer/dysplasia indication | Visible or high-grade dysplasia, multifocal or nonresectable lesions | Colitis-associated dysplasia in colonic CD; often managed similarly to UC |
| Emergency indications | Toxic megacolon, perforation, massive hemorrhage, fulminant colitis | Perforation, uncontrolled hemorrhage, fulminant colitis, sepsis from penetrating disease |
| Typical index operation | Subtotal colectomy with end ileostomy or proctocolectomy with IPAA | Ileocolic resection, segmental resection, or stricturo-plasty |
- Citation: Agrawal H, Gupta N. Surgical interventions in inflammatory bowel disease: Indications, techniques, outcomes, and future directions. World J Gastrointest Pharmacol Ther 2026; 17(2): 118778
- URL: https://www.wjgnet.com/2150-5349/full/v17/i2/118778.htm
- DOI: https://dx.doi.org/10.4292/wjgpt.v17.i2.118778