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Observational Study
©The Author(s) 2025.
World J Gastrointest Pharmacol Ther. Dec 5, 2025; 16(4): 110642
Published online Dec 5, 2025. doi: 10.4292/wjgpt.v16.i4.110642
Table 1 Study population baseline characteristics, n (%)

Adults (n = 21)
Pediatric (n = 24)
Age (years)
mean (SD)42.9 (17.6)9.7 (4.6)
Range (minimum-maximum)19-753-17
Sex
    Female11 (52.4)5 (20.8)
    Male10 (47.6)19 (79.2)
Weight and BMI
    Weight (kg), mean (SD)57.5 (12.8)27.3 (12.7)
    BMI, mean (SD)21.9 (3.4)16.4 (1.9)
Time of parenteral support (years), mean (SD)7 (5.9)7.8 (4.7)
Cause of major intestinal resection
    Vascular disease9 (42.9)0 (0)
    Postoperative complication5 (23.8)0 (0)
    Volvulus3 (14.3)8 (33.3)
    Intestinal atresia2 (9.5)7 (29.2)
    Gastroschisis0 (0)5 (20.8)
    Injury/traumatic2 (9.5)1 (5.6)
    Necrotizing enterocolitis0 (0)1 (4.2)
    Other cause0 (0)2 (8.4)
Anatomy type
    Type 12 (9.5)1 (4.2)
    Type 213 (61.9)16 (66.7)
    Type 36 (28.9)7 (29.2)
Colon in continuity
    Yes19 (90.5)22 (91.7)
    No2 (9.5)2 (8.3)
Remanent colon
    > 0%-25%2 (9.5)2 (8.3)
    > 25%-50%13 (61.9)6 (25)
    > 50%-75%0 (0)6 (25)
    > 75%-100%6 (28.6)9 (37.5)
    Other or not available0 (0)1 (4.2)
Remanent small bowel length (cm), mean (SD)48.2 (40.6)43 (39.8)
Ostomy
    Colostomy0 (0)2 (8.3)
    Jejunostomy1 (4.8)1 (4.2)
    Ileostomy1 (4.8)0 (0)

  • Citation: Solar Muñiz H, Fernández A, Busoni V, Martínez MI, Rumbo C, De Barrio S, Saure C, Balacco M, Buncuga MG, Dlugoszweski C, Manzur A, Rudi L, Matoso MD, Cosentino S, Ussher F, Manzur F, Demarchi J, Malaver E, Brion L, Ungar L. Real-world effectiveness and safety of teduglutide in adult and pediatric patients with short bowel syndrome in Argentina. World J Gastrointest Pharmacol Ther 2025; 16(4): 110642
  • URL: https://www.wjgnet.com/2150-5349/full/v16/i4/110642.htm
  • DOI: https://dx.doi.org/10.4292/wjgpt.v16.i4.110642

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