Electroacupuncture alleviates symptoms and identifies a potential microbial biomarker in patients with constipation-predominant irritable bowel syndrome

Figure 3 Predicted neurotransmitter-related metabolic pathways analyzed by Phylogenetic Investigation of Communities by Reconstruction of Unobserved States 2, compared between healthy controls and irritable bowel syndrome with predominant constipation responders to electroacupuncture, indicating potential microbiome shifts associated with therapeutic response. ACP: Irritable bowel syndrome patients after electroacupuncture; ACP1M: Irritable bowel syndrome patients after electroacupuncture and one-month follow-up; IBS: Irritable bowel syndrome patients.