Electroacupuncture alleviates symptoms and identifies a potential microbial biomarker in patients with constipation-predominant irritable bowel syndrome

Figure 1 Diversity of gut microbiota and their composition in healthy controls, patients with irritable bowel syndrome with predominant constipation at baseline and after electroacupuncture. A: Alpha diversity is presented as boxplots; B: Beta diversities were presented by the principal coordinate analysis plot; C: Differential abundance calculated by Analysis of the Composition of Microbiomes with Bias Correction are presented as bar plots of beta coefficients and standard error of beta. Orange and blue colors represent decrease and increase of gut microbiota respectively, with the corresponding columns. Only taxa with significant associations after being adjusted with the Bonferroni correction are presented. IBS: Irritable bowel syndrome patients; ACP: Irritable bowel syndrome patients after electroacupuncture; PERMANOVA: Permutational multivariate analysis of variance.