Case Control Study
Copyright ©The Author(s) 2020.
World J Gastrointest Pharmacol Ther. Jun 9, 2020; 11(2): 17-24
Published online Jun 9, 2020. doi: 10.4292/wjgpt.v11.i2.17
Table 2 Acromegaly abdominal symptoms and medicine use
Controls (n = 200)Acromegaly patients (n = 50)P value (Fisher’s exact test)
Gastrointestinal symptoms32 (16%)46 (92%)
Abdominal pain19 (9.5%)11(22%)0.4905
Diarrhoea8 (4%)4 (8%)0.2652
Constipation15 (7.5%)34 (68%)< 0.00001b
Medicines
Regular use of anti-secretory (PPI/H2RA)/antacids11 (6.5%)31 (62%)< 0.00001b
Regular use of laxatives6 (3%)46 (92%)< 0.00001b
Regular use of opioid analgesics11 (6.5%)2 (4%)Not statistically significant
Somatostatin analogues-37 (74%)