Gastro-oesophageal reflux disease and eosinophilic oesophagitis: What is the relationship?

doi:10.4291/wjgp.v9.i3.63

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World Journal of Gastrointestinal Pathophysiology

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2150-5330

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Pathophysiol. Oct 25, 2018; 9(3): 63-72
Published online Oct 25, 2018. doi: 10.4291/wjgp.v9.i3.63

Table 2 Diagnostic features of gastro-oesophageal reflux disease and eosinophilic oesophagitis

	GORD	EoE
Endoscopic	Erosive oesophagitis	Trachealization
	Peptic strictures	Felinization
	Hiatus hernia	Whitish exudates
	Barrett’s oesophagus	Longitudinal furrows
		Oedema
		Diffuse oesophageal narrowing
		Narrow-calibre oesophagus
		Oesophageal lacerations
		Loss of mucosal vascular pattern
Histological	Eosinophilia < 10/hpf	Eosinophilia ≥ 15/hpf
		Eosinophilic microabscesses
		Eosinophil degranulation
		Basal cell hyperplasia
		Papillary lengthening
		Superficial layering of eosinophils
		Extracellular eosinophil granules
		Intracytoplasmic keratinocyte vacuolation
		Dilated intracellular spaces
		Lamina propria fibrosis
		Positive intrasqamous IgG4
Motor function	Non-specific	Non-specific

GORD: Gastro-oesophageal reflux disease; EoE: Eosinophilic oesophagitis.

Citation: Wong S, Ruszkiewicz A, Holloway RH, Nguyen NQ. Gastro-oesophageal reflux disease and eosinophilic oesophagitis: What is the relationship? World J Gastrointest Pathophysiol 2018; 9(3): 63-72
URL: https://www.wjgnet.com/2150-5330/full/v9/i3/63.htm
DOI: https://dx.doi.org/10.4291/wjgp.v9.i3.63