Retrospective Cohort Study
Copyright ©The Author(s) 2016.
World J Gastrointest Pathophysiol. Aug 15, 2016; 7(3): 288-295
Published online Aug 15, 2016. doi: 10.4291/wjgp.v7.i3.288
Table 2 Characteristics of the subjects according to the degree of H. pylori infiltration on gastric biopsy n (%)
VariablesMild H. pylori infiltration (n = 14)Moderate H. pylori infiltration (n = 23)Marked H. pylori infiltration (n = 74)P value
Age (yr, mean ± SD)54.7 ± 8.457.7 ± 12.054.7 ± 9.00.428
Gender (male)6 (42.9)16 (69.6)44 (59.5)0.276
Serum anti-H. pylori IgG titer (AU/mL)12.39 (0.36-4.00)3.37 (1.86-4.00)3.95 (0.82-4.00)< 0.001
Serum PG I level (ng/mL, mean ± SD)58.0 ± 19.375.5 ± 32.673.6 ± 28.70.146
Serum PG II level (ng/mL, mean ± SD)15.6 ± 6.322.9 ± 9.522.9 ± 9.20.021
Serum PG I/II ratio (mean ± SD)4.1 ± 1.73.4 ± 1.03.4 ± 1.10.118
Presence of corpus gastric atrophy as reflected by PG assay3 (21.4)5 (21.7)15 (20.3)0.986
Biopsied site (antrum:body or angle:fundus or cardia)1:3:015:7:143:26:50.625
Scores based on Updated Sydney system
Activity (mean ± SD)1.5 ± 0.71.9 ± 0.52.0 ± 0.70.034
Inflammation (mean ± SD)1.9 ± 0.52.0 ± 0.22.1 ± 0.40.052
Atrophy (median with ranges)0.8 (0-3)1.3 (0-3)0.9 (0-3)0.589
Intestinal metaplasia (median with ranges)0.6 (0-3)0.9 (0-3)0.6 (0-3)0.771
Positive HBsAb finding9 (64.3)17 (73.9)52 (70.3)0.824
HBsAb titer (mIU/mL)1174.9 (1-1000)120.7 (1-1000)86.8 (1-1000)0.601
Platelet (× 103/μL, mean ± SD)252.2 ± 41.9231.9 ± 51.9233.2 ± 48.10.375
White blood cell count (× 103/μL, mean ± SD)5688.6 ± 1552.35780.0 ± 1390.95908.0 ± 1678.00.869
Neutrophil (%)55.1 ± 9.354.9 ± 10.345.5 ± 9.10.702
Lymphocyte (%)36.8 ± 8.737.0 ± 9.836.2 ± 8.40.919
Monocyte (%)4.9 ± 1.64.9 ± 2.14.6 ± 1.50.732
Eosinophil (%)2.4 (0-6)2.0 (0-1)1.8 (0-1)0.819
Basophil (%)0.4 (0-1)0.5 (0-1)0.4 (0-5)0.771