Hypoallergenic formula with Lactobacillus rhamnosus GG for babies with colic: A pilot study of recruitment, retention, and fecal biomarkers

Figure 3 Abundance of Lactobacillus rhamnosus and shifts in composition of stool specimens. A: Lactobacillus rhamnosus 16S rDNA sequence abundance in colicky infants at baseline and 14, 42 and 90 d after treatment with LGG (visits 2, 3 and 4). The median, 25^th-75^th percentiles (boxes) and 10^th-90^th percentiles (whiskers) are represented. Black dots represent outliers. ^aP < 0.05 compared to baseline and all other visits, respectively; B: Twins’ bacterial distribution at genus level. The abundance of major bacterial genera in stools of twin infants with colic: baseline (visit 1) and 14, 42 and 90 d after assignment to formula +/- LGG (visits 2, 3 and 4). Only one stool sample was evaluable at visit 1. The percent of abundance of Lactobacillus was indicated as orange box which was increased in LGG+ compared to LGG- at visit 2 (P < 0.05). LGG: Lactobacillus rhamnosus GG.