Serum cytokine profile in patients with hepatitis B e antigen-negative chronic active hepatitis B and inactive hepatitis B virus carriers

doi:10.4291/wjgp.v4.i1.24

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World Journal of Gastrointestinal Pathophysiology

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2150-5330

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Pathophysiol. Feb 15, 2013; 4(1): 24-27
Published online Feb 15, 2013. doi: 10.4291/wjgp.v4.i1.24

Table 2 Cytokine levels in hepatitis B e antigen-negative chronic active hepatitis B patients and asymptomatic hepatitis B virus carriers

Cytokines(pg/mL)	Group A(n = 21)	Group B(n = 13)	P value
IFN-γ	0.3 (0-17.5)	18.3 (0-5137)	0.048
TNF-α	101.3 (0-462.2)	202.6 (0-1044)	NS
IL-1b	98.5 (0-25196)	61.0 (0-11149)	NS
IL-4	285.4 (0-10885)	4.9 (0-4313)	NS
IL-12	154.6 (0-39042)	172.6 (0-10618)	NS
IL-10	0 (0-41.4)	18.6 (0-14393)	0.008
IL-8	314.8 (51.1-32592)	383.0 (67.8-14075)	NS
IL-5	78.4 (0-515.5)	198.0 (0-853.7)	NS
IL-2	158.9 (28.2-126842)	146.4 (29.5-163730)	NS

Data expressed as median (min-max). Group A: Hepatitis B e antigen-negative chronic active hepatitis B patients; Group B: Asymptomatic HBV carriers. NS: Non-significant; IFN-γ: Interferon-γ; TNF-α: Tumor necrosis factor-α; IL: Interleukin.

Citation: Dimitropoulou D, Karakantza M, Theodorou GL, Leonidou L, Assimakopoulos SF, Mouzaki A, Gogos CA. Serum cytokine profile in patients with hepatitis B e antigen-negative chronic active hepatitis B and inactive hepatitis B virus carriers. World J Gastrointest Pathophysiol 2013; 4(1): 24-27
URL: https://www.wjgnet.com/2150-5330/full/v4/i1/24.htm
DOI: https://dx.doi.org/10.4291/wjgp.v4.i1.24