Non-erosive and uncomplicated erosive reflux diseases: Difference in physiopathological and symptom pattern

Table 3 NERD+ vs ERD: pH monitoring

24 h pH monitoring	NERD+	ERD	P value
Number of reflux episodes
Total
mean ± SD	125.67 ± 74.49	162.93 ± 128.1	0.01
Median	118	131
Lasting > 5 min
mean ± SD	4.42 ± 4.9	8.19 ± 7.7	0
Median	3	6
pH < 4
Total time (%)
mean ± SD	9.24 ± 8.1	15.80 ± 14	0
Median	6.8	11
Upright time (%)
mean ± SD	10.20 ± 7.9a	14.20 ± 13b	0.007
Median	7.8	10.7
Supine time (%)
mean ± SD	7.6 ± 12.2a	18.20 ± 20.6b	0
Median	4.1	11.1
DeMeester score
mean ± SD	37.24 ± 32.63	63.38 ± 48.70	0
Median	30.4	48.7

NERD+: Non-erosive reflux disease positive on pH monitoring; ERD: Erosive reflux disease; NS: Non-statistically significative;

^aNERD+: Upright vs supine (P = 0.02);

^bERD Supine vs upright (P = 0.01).