Non-erosive and uncomplicated erosive reflux diseases: Difference in physiopathological and symptom pattern

Table 2 NERD+ vs ERD: manometry study

Manometry	NERD+	ERD	P value
LES
Pressure (mmHg)
mean ± SD	11.18 ± 6.5	9.4 ± 5.3	0.03
Median	9.33	8.5
Total length (cm)
mean ± SD	2.57 ± 0.7	2.44 ± 0.8	NS
Median	3	3
Abdominal length (cm)
mean ± SD	1.13 ± 0.8	1.05 ± 0.9	NS
Median	1	1
Esophageal body
Distal wave amplitude (mmHg)
mean ± SD	80.38 ± 45	75.55 ± 40	NS
Median	70.2	68.3
Proximal wave amplitude (mmHg)
mean ± SD	50.61 ± 20	50.74 ± 21	NS
Median	50	48.65
Distal wave duration (s)
mean ± SD	3.58 ± 1	3.64 ± 0.9	NS
Median	3.45	3.4
Proximal wave duration (s)
mean ± SD	2.83 ± 1	2.92 ± 0.6	NS
Median	2.75	2.75
Effective peristalsis (%)	41 (47.7%)	45 (52.3%)	NS

LES: Lower esophageal sphincter; NERD+: Non-erosive reflux disease positive on pH monitoring; ERD: Erosive reflux disease; NS: Non-statistically significative.