Copyright: ©Author(s) 2026.
World J Gastrointest Pathophysiol. Jun 22, 2026; 17(2): 120603
Published online Jun 22, 2026. doi: 10.4291/wjgp.v17.i2.120603
Published online Jun 22, 2026. doi: 10.4291/wjgp.v17.i2.120603
Table 3 Various liver stiffness measurement cut-off values for predicting risk of hepatocellular carcinoma in patients with cirrhosis with sensitivity, specificity, positive predictive value and negative predictive value, 95%CI
| LSM cut-off in kPa | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Accuracy (%) |
| 30 | 100.0 (91.2-100.0) | 19.3 (13.2-27.3) | 29.4 (22.4-37.6) | 100.0 (85.7-100.0) | 39.6 (32.4-47.4) |
| 35 | 97.5 (87.1-99.6) | 46.2 (37.5-55.2) | 37.9 (29.1-47.5) | 98.2 (90.6-99.7) | 59.1 (51.4-66.5) |
| 40 | 97.5 (87.1-99.6) | 52.1 (43.2-60.9) | 40.6 (31.3–50.6) | 98.4 (91.5–99.7) | 63.5 (55.8-70.6) |
| 45 | 95.0 (83.5-98.6) | 67.2 (58.4-75.0) | 49.4 (38.5-60.3) | 97.6 (91.5-99.3) | 74.2 (66.9-80.4) |
| 47 | 95.0 (83.5-98.6) | 76.5 (68.1-83.2) | 57.6 (45.6-68.8) | 97.8 (92.5-99.4) | 81.1 (74.3-86.5) |
| 50 | 77.5 (62.5-87.7) | 82.4 (74.5-88.2) | 59.6 (46.1-71.8) | 91.6 (84.8-95.5) | 81.1 (74.3-86.5) |
| 55 | 57.5 (42.2-71.5) | 86.6 (79.3-91.6) | 59.0 (43.4-72.9) | 85.8 (78.5-91.0) | 79.2 (72.3-84.8) |
| 60 | 42.5 (28.5-57.8) | 91.6 (85.2-95.4) | 63.0 (44.2-78.5) | 82.6 (75.2-88.1) | 79.2 (72.3-84.8) |
| 65 | 32.5 (20.1-48.0) | 95.8 (90.5-98.2) | 72.2 (49.1-87.5) | 80.9 (73.6-86.5) | 79.9 (73.0-85.4) |
| 70 | 20.0 (10.5-34.8) | 97.5 (92.8-99.1) | 72.7 (43.4-90.3) | 78.4 (71.1-84.2) | 78.0 (70.9-83.7) |
| 75 | 7.5 (2.6-19.9) | 100.0 (96.9-100.0) | 100.0 (43.9-100.0) | 76.3 (69.0-82.3) | 76.7 (69.6-82.6) |
- Citation: Mehta V, Goyal MK, Gupta YK, Gupta A, Khubber M, Sehgal T, Mehta P, Goyal O. Liver stiffness at baseline as a marker of hepatocellular carcinoma in cirrhosis: A matched analysis. World J Gastrointest Pathophysiol 2026; 17(2): 120603
- URL: https://www.wjgnet.com/2150-5330/full/v17/i2/120603.htm
- DOI: https://dx.doi.org/10.4291/wjgp.v17.i2.120603