From esophagus to colon: A narrative review of eosinophilic gastrointestinal disorders

doi:10.4291/wjgp.v17.i1.115307

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World Journal of Gastrointestinal Pathophysiology

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2150-5330

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Pathophysiol. Mar 22, 2026; 17(1): 115307
Published online Mar 22, 2026. doi: 10.4291/wjgp.v17.i1.115307

Table 3 Differential diagnoses of colonic eosinophilia

Parasitic infections	Strongyloides stercoralis, Enterobius vermicularis, Trichuris trichiura
Drugs	Clozapine, carbamazepine, rifampicin, gold, NSAIDs, tacrolimus
Transplant-related	Prolonged immunosuppression (e.g., tacrolimus in liver transplant recipients)
Systemic disorders	Hypereosinophilic syndrome, Churg-Strauss, autoimmune diseases
IBD overlap	Eosinophilic infiltration may mimic or precede ulcerative colitis
Others	Radiation colitis, Tolosa-hunt syndrome

IBD: Inflammatory bowel diseases; NSAIDs: Nonsteroidal anti-inflammatory drugs.

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Citation: Qasim A, Zacharia GS, Veena F, Kandhi SD, Patel H. From esophagus to colon: A narrative review of eosinophilic gastrointestinal disorders. World J Gastrointest Pathophysiol 2026; 17(1): 115307
URL: https://www.wjgnet.com/2150-5330/full/v17/i1/115307.htm
DOI: https://dx.doi.org/10.4291/wjgp.v17.i1.115307

Qasim A, Zacharia GS, Veena F, Kandhi SD, Patel H. From esophagus to colon: A narrative review of eosinophilic gastrointestinal disorders. World J Gastrointest Pathophysiol 2026; 17(1): 115307 [PMID: 41884200 DOI: 10.4291/wjgp.v17.i1.115307]

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