Constipation in critically ill adults

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World Journal of Gastrointestinal Pathophysiology

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2150-5330

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Pathophysiol. Dec 22, 2025; 16(4): 112019
Published online Dec 22, 2025. doi: 10.4291/wjgp.v16.i4.112019

Table 2 Contributing factors to constipation in critically ill adults

Category	Contributing factors
Patient-related factors	Advanced age, prior abdominal surgery, immobility
Disease-related factors	Systemic	Acute kidney injury, sepsis, shock
	Metabolic	Diabetes mellitus, hyper/hypothyroidism, electrolyte imbalances
	Neurological	Spinal cord injury, stroke, Parkinson’s disease, multiple sclerosis, autonomic neuropathy
	Myopathies	Amyloidosis, scleroderma
	Psychological	Depression, anxiety, eating disorders
	Mechanical	Colorectal cancer, strictures, rectocele
Medication-related factors	Polypharmacy
	Opioids
	Sedatives
	Anticholinergics, including antidepressants and antipsychotics
	Antihypertensives, including calcium-channel blockers
	Diuretics
Nutrition-related factors	NPO status, delayed enteral feeding, inadequate fiber intake, dehydration

NPO: Nothing by mouth.

Citation: Kim Y, See KC. Constipation in critically ill adults. World J Gastrointest Pathophysiol 2025; 16(4): 112019
URL: https://www.wjgnet.com/2150-5330/full/v16/i4/112019.htm
DOI: https://dx.doi.org/10.4291/wjgp.v16.i4.112019

Kim Y, See KC. Constipation in critically ill adults. World J Gastrointest Pathophysiol 2025; 16(4): 112019 [PMID: 41479858 DOI: 10.4291/wjgp.v16.i4.112019]

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