©The Author(s) 2025.
World J Gastrointest Pathophysiol. Sep 22, 2025; 16(3): 108952
Published online Sep 22, 2025. doi: 10.4291/wjgp.v16.i3.108952
Published online Sep 22, 2025. doi: 10.4291/wjgp.v16.i3.108952
Figure 1 Gut-skin axis as part of the broader skin-gut-brain-immune system axis.
The skin, gut, brain, and immune system are intricately inter connected, engaging in a dynamic and bidirectional communication network. This cross-talk includes skin–gut, skin–immune, gut–brain, and gut–immune interactions. At the heart of this complex axis lies the microbiome, orchestrating the interplay across these systems and playing a pivotal role in health and disease.
- Citation: Singla N, Singla K, Attauabi M, Aggarwal D. Gut-skin axis: Emerging insights for gastroenterologists-a narrative review. World J Gastrointest Pathophysiol 2025; 16(3): 108952
- URL: https://www.wjgnet.com/2150-5330/full/v16/i3/108952.htm
- DOI: https://dx.doi.org/10.4291/wjgp.v16.i3.108952