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World Journal of Gastrointestinal Pathophysiology
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2150-5330
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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©The Author(s) 2025.
World J Gastrointest Pathophysiol. Sep 22, 2025; 16(3): 108952
Published online Sep 22, 2025. doi: 10.4291/wjgp.v16.i3.108952
Table 4 Gut-skin axis–linked diseases and their microbial dysbiosis profiles
Condition
Gut microbiome changes
Skin microbiome changes
Atopic dermatitis↓Bifidobacteria, ↓F. prausnitzii, ↑Enterobacteriaceae↑S. aureus, ↓microbial diversity
Psoriasis↑Ruminococcus, ↓Akkermansia muciniphila, ↓Faecalibacterium prausnitzii↑Corynebacterium, ↑Streptococcus
Rosacea↑Prevotella intermedia, ↓Cutibacterium↑Demodex folliculorum, ↑Gordonia
Hidradenitis suppurativa↑Porphyromonas, ↑Prevotella, ↓diversity↑anaerobes in lesions, ↓alpha diversity
Celiac disease↑Proteobacteria, ↓Lactobacillus, ↑CandidaAssociated with dermatitis herpetiformis
Seborrheic dermatitisAltered lipid metabolism-related bacteria (e.g., ↑Enterobacteriaceae)↑Malassezia species (esp. M. restricta), altered yeast load
Acne vulgaris↓Lactobacillus, ↑Proteobacteria, ↓diversity↑Cutibacterium acnes (formerly Propionibacterium acnes)
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