P2X7 receptor antagonist recovers ileum myenteric neurons after experimental ulcerative colitis

doi:10.4291/wjgp.v11.i4.84

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World Journal of Gastrointestinal Pathophysiology

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2150-5330

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Pathophysiol. Jun 20, 2020; 11(4): 84-103
Published online Jun 20, 2020. doi: 10.4291/wjgp.v11.i4.84

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Figure 6 Colocalization of the P2X7 receptor with glial fibrillary acidic protein in the rat ileum myenteric plexus in the sham, 2,4,6-trinitrobenzene sulfonic acid and brilliant blue G groups. A-C: Sham group; D-F: 2,4,6-trinitrobenzene group; G-I: Brilliant blue G group. GFAP immunoreactivity (red; A, D, and G) colocalized with P2X7 immunoreactivity (green; B, E and H). Single arrows indicate double-labeled enteric glial cells. Scale bars = 50 µm. GFAP: Glial fibrillary acidic protein; TNBS: 2,4,6-trinitrobenzene sulfonic acid; BBG: Brilliant blue G.

Citation: Souza RF, Evangelinellis MM, Mendes CE, Righetti M, Lourenço MCS, Castelucci P. P2X7 receptor antagonist recovers ileum myenteric neurons after experimental ulcerative colitis. World J Gastrointest Pathophysiol 2020; 11(4): 84-103
URL: https://www.wjgnet.com/2150-5330/full/v11/i4/84.htm
DOI: https://dx.doi.org/10.4291/wjgp.v11.i4.84