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Copyright ©The Author(s) 2019.
World J Gastrointest Pathophysiol. Jan 5, 2019; 10(1): 1-10
Published online Jan 5, 2019. doi: 10.4291/wjgp.v10.i1.1
Table 1 mACE2-rAAV2/8 therapy increased hepatic ACE2 expression, resulting in a marked reduction in biliary fibrosis in a long-term model of chronic biliary fibrosis (Mdr2-KO mice)
Stage of the diseaseHepatic ACE2 expression, foldLiver fibrosis reduction, %
Early: 3-6 mo6050%
Advanced: 7-9 mo16080%