Copyright
©The Author(s) 2016.
World J Gastrointest Pathophysiol. May 15, 2016; 7(2): 218-222
Published online May 15, 2016. doi: 10.4291/wjgp.v7.i2.218
Published online May 15, 2016. doi: 10.4291/wjgp.v7.i2.218
Figure 1 Schematics showing the maturation of mesothelin protein.
The primary product of the full-ERC/mesothelin gene is a 71-kDa precursor protein. This protein is physiologically cleaved, releasing a 31-kDa fragment, N-ERC/mesothelin, into the blood. MPF: Megakaryocyte potentiating factor; SMRP: Soluble mesothelin-related peptide; GPI: Glycosylphosphatidylinositol.
Figure 2 The expression of mesothelin in gastric cancer.
A: Luminal membrane expression. The entire circumference of the cell membrane was stained; B: “Cytoplasmic expression” with granular cytoplasmic staining in cancer cells.
- Citation: Einama T, Kawamata F, Kamachi H, Nishihara H, Homma S, Matsuzawa F, Mizukami T, Konishi Y, Tahara M, Kamiyama T, Hino O, Taketomi A, Todo S. Clinical impacts of mesothelin expression in gastrointestinal carcinomas. World J Gastrointest Pathophysiol 2016; 7(2): 218-222
- URL: https://www.wjgnet.com/2150-5330/full/v7/i2/218.htm
- DOI: https://dx.doi.org/10.4291/wjgp.v7.i2.218