Cerebellum and neurodegenerative diseases: Beyond conventional magnetic resonance imaging

Figure 4 Motor training-dependent functional magnetic resonance imaging signal changes in healthy volunteers and in MS patients. Maps of training-related functional magnetic resonance imaging signal changes are reported in healthy volunteers (indicated as controls) and in patients (Z > 2.3, P < 0.05, cluster corrected). Comparison between patients and controls show a higher signal reduction in the patients in regions corresponding to the secondary visual areas (V2 and V4) and in the cerebellum (lobule V-VI) (from Ref. [100]). V5: Visual cortex; R5: Right hemisphere; fMRI: Functional magnetic resonance imaging.