Imaging pancreatic islet cells by positron emission tomography

Figure 4 Representative ¹⁸F-TTCO-Cys⁴⁰-exendin-4 positron emission tomography images in NOD/SCID mice. A: Representative microPET images of 18F-TTCOCys40-exendin-4 (top) and blocking (bottom) for NOD/SCID mice with INS-1; B: Tumor uptakes between control and blocking groups; C: Tumor to organs ratios of radiotracer at different time points p.i.; D: Representative microPET images of tracer in NOD/SCID mice transplanted with human islets into liver (top) and control mice (bottom) at different time points p.i.; E: Liver uptake between intraportal islet transplantation and sham control groups; F: MicroPET mages of mice transplanted with human islets (Left: Control; Middle: Blocking and sham control mice at 1 h p.i.). Reprinted with permission from Ref.[23]. PET: Positron emission tomography.