Angiographic and volumetric effects of mammalian target of rapamycin inhibitors on angiomyolipomas in tuberous sclerosis

Figure 1 Examples of volumetric analysis on computed tomography and magnetic resonance imaging. A: Coronal “fat-only” maps created from in- and opposed-phase gradient recalled imaging were used to measure macroscopic fat volumes within AMLs; B: Segmentation of tumoral vascularity (automatically generated regions of interest demarcated by pink line) from post-contrast subtraction imaging was used to calculate tumor vascular volumes; C: Histogram analysis from CT was used to calculate tumoral fat and vascular content (pseudocoloring depicts fatty tissue as red and vascular tissue as yellow). CT: Computed tomography; AML: Angiomyolipoma.