Diffusion-weighted imaging of the liver: Current applications

Table 1 Detection of fibrosis using diffusion-weighted imaging

	Tesla	Respiratory	Staging	ROI setting	b-value	Diagnostic accuracy of fibrosis F3 or grater
						AUC	Sensitivity	Specificity
Cece et al[91]	1.5	BH	MTAVIR	5 ROIs, Both	0, 500, 1000	0.888	92.9	79.4
Taouli et al[92]	1.5	BH	MTAVIR	4 ROIs, Both	0, 50	0.717	40	100
					0, 300	0.716	50	94.7
					0, 500	0.835	70	85
					0, 700	0.901	66.7	100
					0, 1000	0.832	80	90
					0, 50, 300, 500, 700, 1000	0.896	88.9	80
Kocakoc et al[93]	1.5	BH	Ishak	3 ROIs, Both	100, 600, 1000	0.759	56.5	99.3
Wu et al[47]	3	RT	MTAVIR	5 ROIs, Right	0, 10, 20, 30, 40, 50, 60, 70, 80, 90, 100, 200, 300, 400, 500, 1000	0.684
Chung et al[48]	1.5	RT	MTAVIR	6 ROIs, Right	0, 100, 200, 900	0.768
					0, 30, 60, 100, 150, 200, 900	0.764
					0, 30, 60, 100, 150, 200, 400, 600, 900	0.754	65.5	82.1
Ding et al[94]	1.5	FB	New Inuyama	Whole right lobe	0, 500	0.61	30.4	90.6
Feier et al[43]	3	NA	MTAVIR	1 ROI, Right	50, 300, 600	0.77	81.08	72.5
Fujimoto et al[95]	1.5	NA	MTAVIR	4 ROIs, Right	0, 1000 (entropy ADC)	0.926	87	84
Do et al[46]	1.5	BT	Ludwig	4 ROIs, Right	0, 50, 500 (normalized ADC)	0.689	56	71
Bonekamp et al[96]	1.5	BT	MTAVIR	9 ROIs, Both	0, 750	0.8	83.9	68.5
Wang et al[44]	1.5	NA	MTAVIR	3 ROIs, Right	50, 500, 1000	0.84	88	76
Lewin et al[41]	1.5	RT	MTAVIR	3 ROIs, Right	0, 200, 400, 800	0.92	87	87
Sandrosegaran et al[40]	1.5	BH		2 ROIs, Both	50, 400	0.656	51.7	71.4

BH: Breath-hold; RT: Respiratory gating.