Perfusion computed tomography in renal cell carcinoma

Figure 1 Perfusion computed tomography in normal renal parenchyma vs renal cell carcinoma in a 50-year-old man with left renal cell carcinoma (clear cell type). A: Contrast computed tomography (CT) images showed a large, hyperenhancing mass in left kidney with central necrosis (arrow). Colour-coded perfusion maps show various perfusion parameters in normal right kidney and diseased left kidney. Red being the region with highest perfusion parameter with purple being the least; B: Time attenuation curve and the perfusion parameters in normal right kidney. Normal renal parenchyma is seen to have high perfusion in the range of 255 mL/100 mL per minute; C: Time attenuation curve and perfusion parameters in the left renal cell carcinoma. There is delayed wash-out of contrast in the region of the tumour as depicted in the graph. MIP: Maximum peak intensity; TTP: Time to peak; BF: Blood flow; BV: Blood volume; MTT: Mean transit time; PMB: Permeanbility.