Middle cerebellar peduncles: Magnetic resonance imaging and pathophysiologic correlate

Figure 3 Progressive multifocal leucoencephalopathy. HIV patient with + JC virus on PCR-CSF. Bilateral involvement of MCP on axial FLAIR (A); with no enhancement (not shown); Axial FLAIR (B) and axial DWI (C) images show asymmetric confluent areas of increased signal in the subcortical WM with involvement of the u-fibers (arrow) and linear “edge” on DWI (arrow on C) consistent with advancing demyelinated edge; D: Three months f/u images better depict involvement of u-fibers (white arrow) as well as progression of WM disease with formation of small central cavitation/micro cyst, characteristic of PML (black arrow). PML: Progressive multifocal leucoencephalopathy; MCP: Middle cerebellar peduncles; CSF: Cerebrospinal fluid; DWI: Diffusion weighted-imaging; PCR: Polymerase chain reaction; HIV: Human immunodeficiency virus.