Diffusion-weighted imaging of pancreatic cancer

Table 3 Data derived from studies that have evaluated apparent diffusion coefficient quantification of pancreatic ductal adenocarcinomas with different degree of differentiation

Ref.	No. of patients	Field strength (T)	b-values(s/mm2)	Mean ± SD ADC(× 10-3 mm2/s)	P value
Wang et al[20]	21	1.5	0, 500	2.10 ± 0.42 (MD-WD)	< 0.05
				1.46 ± 0.17 (PD)
Legrand et al[21]	22	1.5 or 3	Multiple1	1.43 ± 0.12 (WD)	0.05
				1.94 ± 0.62 (MD-PD)
Muraoka et al[44]	10	1.5	0, 500	1.88 ± 0.39 (loose fibrosis)	< 0.05
				1.01 ± 0.29 (dense fibrosis)
Rosenkrantz et al[45]	30	1.5	0, 500	1.78 ± 0.33/1.75 ± 0.49 (MD-WD)2	NS
				1.69 ± 0.36/1.62 ± 0.33 (PD)2
Fukukura et al[46]	92	3	0, 1000	1.10 ± 0.09 (high cellularity)	< 0.05
				1.25 ± 0.18 (low cellularity)

¹0, 50, 200, 400, 600, 800 s/mm²;

²Two readers. T: Tesla; WD: Well differentiated PDAC; MD: Moderately differentiated PDAC; PD: Poorly differentiated PDAC; ADC: Apparent diffusion coefficient; PDAC: Pancreatic ductal adenocarcinoma; NS: Not statistically significant.