Nuclear imaging in detection and monitoring of cardiotoxicity

doi:10.4329/wjr.v6.i7.486

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Jul 28, 2014 (publication date) through Apr 22, 2024

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World Journal of Radiology

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1949-8470

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Radiol. Jul 28, 2014; 6(7): 486-492
Published online Jul 28, 2014. doi: 10.4329/wjr.v6.i7.486

Table 1 Radiotracer for cardiac nuclear imaging

Technique	Tracer	Action
SPECT
	^99mTc-erythrocyte	Contractile function
	¹¹¹In-antimyosin	Imaging necrosis/cell death
	¹²³I-MIBG	Neuronal imaging(presynaptic uptake and storage)
	¹¹¹In-Tz	Therapeutic target imaging
	^99mTc-annessin V	Imaging necrosis/cell death
	¹²³I-BMIPP	Fatty acid use
PET
	¹⁸F-FDG	Glucose metabolism
	Presynaptic tracers	Visualize inhibition of neurotransmission
	true catecholamines
	¹⁸F-6-fluorodopamine
	¹¹C-epinephrine
	catecholamine analogs	False neurotransmitters
	¹¹C-HED
	¹¹C-phenylephrine
	¹⁸F-6-fluoro-metaraminol
	Postsynaptic tracers	Visualize transmission of sympathetic signal to target tissue
	¹¹C-CGP12177
	¹¹C-CGP12388
	¹¹C-GB67

SPECT: Single photon emission computed tomography; PET: Positron emission tomography; HED: Hydroxyephedrine; FDG: Fluorodeoxyglucose;

¹²³I-BMIPP: ¹²³I-15-(p-iodophenyl)-3-(R,S)-methylpentadecanoic acid.

Citation: D’Amore C, Gargiulo P, Paolillo S, Pellegrino AM, Formisano T, Mariniello A, Della Ratta G, Iardino E, D’Amato M, La Mura L, Fabiani I, Fusco F, Perrone Filardi P. Nuclear imaging in detection and monitoring of cardiotoxicity. World J Radiol 2014; 6(7): 486-492
URL: https://www.wjgnet.com/1949-8470/full/v6/i7/486.htm
DOI: https://dx.doi.org/10.4329/wjr.v6.i7.486