Evaluation of cancer treatment in the abdomen: Trends and advances

Table 2 Traditional response evaluation criteria of solid tumors

Criteria	WHO[7]	RECIST[9]	RECIST 1.2[12]
CR	Disappearance of all known lesions	Disappearance of all target and non-target lesions - confirm at 4 wk	Disappearance of all target and non- target legions1
PR	≥ 50% decrease in sum of products of all lesions - confirm at 4 wk; no new lesions; no progression of any lesions	≥ 30% decrease from the baseline of the sum of max diameter of all lesions - confirm at 4 wk; no new lesions; no progression	≥ 30% decrease from the baseline of the sum of max diameter of all lesions; no new lesions; no progression1
SD	Neither PR nor PD	Neither PR nor PD	Neither PR nor PD
PD	≥ 25% increase of a single lesion over the smallest measurement or any new lesions	≥ 20% increase over the smallest sum of maximum diameter observed or any new lesions	≥ 20% increase over the smallest sum of maximum diameter and at least 5 mm increase or any new lesions

¹Confirmation at 4 wk required only for non-randomized trials with the primary end-point of response. CR: Complete response; PR: Partial response; PD: Progressive disease; SD: Stable disease; WHO: World Health Organization; RECIST: Response Evaluation of Criteria in Solid Tumors.