Comparing the reliability of three software programmes for manual and (semi-)automatic volumetry in healthy livers

doi:10.4329/wjr.123720

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World Journal of Radiology

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1949-8470

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World J Radiol. Sep 28, 2026; 18(9): 123720
Published online Sep 28, 2026. doi: 10.4329/wjr.123720

Table 2 Liver segmentation volumes from the observers and n = 30 scans, median (interquartile range)

Item	Observer 1	Observer 2	P value	Median percent difference between observers
OsiriX^®
TLV	1523 (1436-1846)	1513 (1422-1812)	0.019	1.4 (-0.7 to 2.5)
SII/III	289 (228-349)	287 (222-347)	0.020	-4.4 (-8.4 to 0.8)
Time in secs	480 (420-600)	660 (540-720)	0.013	-
Syngo.via
TLV	1524 (1392-1873)	1544 (1417-1894)	< 0.001	-0.9 (-2.2 to 0.0)
SII/III	253 (215-290)	282 (215-329)	0.002	-6.4 (-13.9 to 1.0)
Time in secs	390 (255-420)	180 (180-240)	< 0.001	-
Synapse 3D
TLV	1525 (1428-1945)	1530 (1463-1955)	0.006	-0.13 (-1.7 to 1.3)
SII/III	284 (236-350)	316 (263-367)	< 0.001	-10.4 (-13.8 to 6.1)
Time in secs	240 (180-300)	180 (120-180)	0.003	-

TLV: Total liver volume; SII/III: Segment II/III.

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Citation: van der Velden AL, Knapen RRMM, James S, Rahmani H, Brecheisen R, van Kuijk SMJ, Wildberger JE, van Dam RM, van der Leij C. Comparing the reliability of three software programmes for manual and (semi-)automatic volumetry in healthy livers. World J Radiol 2026; 18(9): 123720
URL: https://www.wjgnet.com/1949-8470/full/v18/i9/123720.htm
DOI: https://dx.doi.org/10.4329/wjr.123720

van der Velden AL, Knapen RRMM, James S, Rahmani H, Brecheisen R, van Kuijk SMJ, Wildberger JE, van Dam RM, van der Leij C. Comparing the reliability of three software programmes for manual and (semi-)automatic volumetry in healthy livers. World J Radiol 2026; 18(9): 123720 [DOI: 10.4329/wjr.123720]

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