Development and validation of a clinical factor-based nomogram for predicting imaging-defined cardiopulmonary abnormality risk in an asymptomatic screening population

doi:10.4329/wjr.123894

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World Journal of Radiology

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1949-8470

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Radiol. Jul 28, 2026; 18(7): 123894
Published online Jul 28, 2026. doi: 10.4329/wjr.123894

Table 2 Allocation of training and validation sets among 1035 asymptomatic health examination individuals aged 40 years and above, n (%)

Index	Training set (n = 724)	Validation set (n = 311)	t/χ²/z	P value
Age	52.481 ± 7.874	52.984 ± 8.247	-0.929	0.353
BMI	24.255 ± 2.983	24.220 ± 3.173	0.168	0.866
Sex	-	-	1.716	0.190
Male	466 (64.365)	214 (68.810)	-	-
Female	258 (35.635)	97 (31.190)	-	-
Metabolic status	-	-	0.070	0.791
Abnormal	369 (50.967)	155 (49.839)	-	-
Normal	355 (49.033)	156 (50.161)	-	-
Smoking history	-	-	5.055	0.168
Non-smoker	335 (46.271)	130 (41.801)	-	-
Mild (smoking index ≤ 200)	85 (11.740)	49 (15.756)	-	-
Moderate (200 < smoking index < 400)	68 (9.392)	23 (7.395)	-	-
Heavy (smoking index ≥ 400)	236 (32.597)	109 (35.048)	-	-
Alcohol consumption history	-	-	3.908	0.419
Non-drinker	394 (54.420)	163 (52.412)	-	-
Rarely (< 1/month)	154 (21.271)	57 (18.328)	-	-
Light (2-4/month)	95 (13.122)	50 (16.077)	-	-
Moderate (2-3/week)	38 (5.249)	16 (5.145)	-	-
Heavy (≥ 4/week)	43 (5.939)	25 (8.039)	-	-
Work style	-	-	1.285	0.526
Sedentary behavior	254 (35.083)	114 (36.656)	-	-
Light physical activity	157 (21.685)	74 (23.794)	-	-
Moderate-to-high physical activity	313 (43.232)	123 (39.550)	-	-
High-oil high-salt diet	-	-	2.127	0.145
No	611 (84.392)	274 (88.103)	-	-
Yes	113 (15.608)	37 (11.897)	-	-
Sleep duration	-	-	1.514	0.469
< 6 hours	36 (4.972)	21 (6.752)	-	-
6-8 hours	381 (52.624)	165 (53.055)	-	-
> 8 hours	307 (42.403)	125 (40.193)	-	-
NYHA class	-	-	3.284	0.350
NYHA Class I	679 (93.785)	290 (93.248)	-	-
NYHA Class II	41 (5.663)	19 (6.109)	-	-
NYHA Class III	3 (0.414)	0 (0.000)	-	-
NYHA Class IV	1 (0.138)	2 (0.643)	-	-
Family history of heart disease	-	-	0.200	0.655
No	451 (62.293)	199 (63.987)	-	-
Yes	273 (37.707)	112 (36.013)	-	-
Occupational exposure history	-	-	0.136	0.713
No	690 (95.304)	294 (94.534)	-	-
Yes	34 (4.696)	17 (5.466)	-	-
Family history of lung cancer	-	-	0.035	0.852
No	683 (94.337)	295 (94.855)	-	-
Yes	41 (5.663)	16 (5.145)	-	-

No statistically significant differences were observed between the training and validation sets for any variable (all P > 0.05), indicating adequate balance of random allocation. NYHA: New York Heart Association; BMI: Body mass index.

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Citation: He ZY, Zhan ZW, Zhou LJ, Tang J, Chen C, Yang QJ, Tian Q, Wang XH. Development and validation of a clinical factor-based nomogram for predicting imaging-defined cardiopulmonary abnormality risk in an asymptomatic screening population. World J Radiol 2026; 18(7): 123894
URL: https://www.wjgnet.com/1949-8470/full/v18/i7/123894.htm
DOI: https://dx.doi.org/10.4329/wjr.123894

He ZY, Zhan ZW, Zhou LJ, Tang J, Chen C, Yang QJ, Tian Q, Wang XH. Development and validation of a clinical factor-based nomogram for predicting imaging-defined cardiopulmonary abnormality risk in an asymptomatic screening population. World J Radiol 2026; 18(7): 123894 [PMID: 42529724 DOI: 10.4329/wjr.123894]

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