Predictive value of second-trimester ophthalmic artery Doppler for identifying women at risk for preeclampsia

Table 6 Diagnostic performance of ophthalmic artery Doppler parameters for predicting preeclampsia

Parameter	Low RI	Low P1	Low PI	High P2	High PR
Sensitivity (95%CI), %	100 (63.1–100)	25.0 (3.2–65.1)	75.0 (34.9–96.8)	100 (63.1–100)	100 (63.1–100)
Specificity (95%CI), %	53.7 (42.3–64.8)	97.6 (91.5–99.7)	71.9 (60.9–81.3)	14.6 (7.8–24.2)	90.2 (81.7–95.7)
AUC (95%CI)	0.77 (0.7–0.9)	0.6 (0.5–0.7)	0.7 (0.6–0.8)	0.6 (0.5–0.7)	0.9 (0.8–0.9)
Positive predictive value (95%CI), %	17.4 (7.8–31.4)	50.0 (6.8–93.2)	20.7 (7.9–39.7)	10.3 (4.5–19.2)	50.0 (24.6–75.4)
Negative predictive value (95%CI), %	100 (91.9–100)	93.0 (85.4–97.4)	96.7 (88.7–99.6)	100.0 (73.5–100.0)	100.0 (95.1–100.0)
Diagnostic accuracy, %	57.8	91.1	72.2	22.2	91.1%

AUC: Area under the curve; CI: Confidence interval; P1: First systolic peak velocity; P2: Second systolic peak velocity; PI: Pulsatility index; PR: Peak ratio; RI: Resistive index.